[Wed Aug 24 19:01:45 2016] >Input file: TM4JTCCGD.pdb >TM segments: B458-476_B517-536_B548-567_B583-609_B615-636_B679-698 MAIDEN score = -51.7199 Below is the ranking list of the residue pairs and their related pseudo-energy (the lower, the better). This includes inter-chain residue pairs. The maximum (least favorable) pairwise energy value has been set to 10. See the MAIDEN software article: Postic,G., Ghouzam,Y. and Gelly,J.C. (2015) Biochimie, 115, 155–161. ----------- ---------------- BBeads pair Empirical energy ----------- ---------------- P560B-R588B 0.919741036006759 V556B-R591B 0.895786657783856 F633B-V681B 0.895269884630705 P560B-R591B 0.829615880647092 F625B-T692B 0.822883209440344 V556B-R594B 0.805361928620387 E618B-V697B 0.73324777221566 I468B-K597B 0.699982522229684 I553B-F596B 0.672539486201318 V556B-L593B 0.660059531286215 L622B-P696B 0.628568106167613 F633B-C685B 0.61966435720586 R617B-L622B 0.610145852253511 R600B-L605B 0.591250146250699 I558B-R594B 0.579578732671602 I555B-R594B 0.577516972752834 R617B-I623B 0.576876437812865 T564B-V584B 0.569478131448306 I468B-R594B 0.56890697741619 K603B-L608B 0.554749348206127 I525B-I558B 0.552896047665973 L621B-P696B 0.547860171725166 I459B-S464B 0.546662173012298 P560B-F587B 0.52899734568556 F528B-A557B 0.528455911003048 A636B-V681B 0.518732170381199 S474B-F517B 0.511106116881076 L619B-P696B 0.505846795452346 L622B-I693B 0.498770354786995 M550B-K597B 0.49480091929705 I553B-R594B 0.479270460130522 I559B-R588B 0.474737737000183 D554B-F596B 0.466753722959307 I553B-L593B 0.464633850162737 S471B-V520B 0.458424802851608 V583B-R588B 0.447824273941661 I470B-F475B 0.438573363566496 V467B-C524B 0.428055699636191 I526B-E531B 0.427584857304691 I553B-K597B 0.422467036031078 V630B-S635B 0.418692372912945 R458B-V463B 0.41638776606911 E531B-D554B 0.411962591460991 I559B-F587B 0.402814048621905 H601B-Q606B 0.400201967309439 I468B-I595B 0.392661445744215 K679B-L684B 0.392288354718866 L469B-R594B 0.389960856899573 Y562B-Q585B 0.386162894555931 W527B-F532B 0.384542488940493 A557B-M590B 0.376215013509247 P560B-M590B 0.357753699317898 V681B-A686B 0.352563258520924 E618B-I623B 0.350459179221797 D554B-R591B 0.34747001859807 R535B-D554B 0.342472136354846 V465B-L598B 0.336230280173447 K597B-Q606B 0.332740767038503 F517B-T522B 0.320012301410259 F528B-I558B 0.317382220036235 A557B-L593B 0.31630216557203 I525B-F530B 0.314332049456902 S529B-K597B 0.305702301944981 A636B-S683B 0.302295072418835 E521B-I526B 0.301443364504209 A557B-I592B 0.300049666882679 L598B-L605B 0.298458168575516 L622B-T692B 0.298253754776677 E531B-F536B 0.296530655248526 S635B-G682B 0.294706219418923 M550B-Q606B 0.29194142148757 M466B-R600B 0.287384605257334 V467B-V520B 0.284773437250405 I525B-A557B 0.283888554127356 F530B-R535B 0.283205170351057 A461B-S602B 0.282540778367905 S471B-R594B 0.281211543824782 V467B-D554B 0.280845437516924 V563B-V583B 0.27768960918477 R458B-M466B 0.276253379902772 I631B-A636B 0.268333510855405 G620B-L695B 0.263662749773241 E531B-H601B 0.25964198160644 N551B-S599B 0.257481648728913 A461B-S599B 0.251222084258726 Y562B-L567B 0.248680603307815 M466B-R594B 0.248389848095646 E521B-P560B 0.246851503594011 I460B-M466B 0.244135952209867 P560B-L593B 0.240927971795677 S464B-L598B 0.228305985208276 M550B-R600B 0.221793028003216 V473B-I595B 0.220005057200088 S471B-S529B 0.219593495272424 D554B-R600B 0.216657692337964 I468B-C476B 0.21581269630462 F627B-A688B 0.215473965246989 C524B-I555B 0.213135569163556 G620B-V697B 0.212494264366898 V630B-G682B 0.21219621938474 Y561B-R588B 0.210332434165684 C685B-I693B 0.208167840578325 L567B-V583B 0.206435394463377 S635B-K679B 0.206231081694429 V465B-F528B 0.205933815949977 V463B-F528B 0.20547619553179 T522B-T564B 0.204379101958628 F530B-A557B 0.203092693111875 W527B-I555B 0.202118871160993 V465B-F596B 0.201686471174144 G629B-L691B 0.200869056321476 R600B-Q606B 0.199892971822435 F625B-V690B 0.199387891181909 I552B-A557B 0.198577111004349 N548B-R600B 0.196551733968183 N551B-R594B 0.195373481886649 I525B-T564B 0.194918524663066 L619B-T692B 0.194863652634802 I460B-V465B 0.193782802211753 R535B-N548B 0.193648522452191 F532B-V556B 0.193336644443368 I559B-T564B 0.19311368881353 M616B-L621B 0.192204524230284 C524B-I559B 0.189499508171452 L632B-V681B 0.189169395663153 S464B-M550B 0.188049483101697 F518B-Y562B 0.187803631234253 R535B-M550B 0.186336379919076 S474B-P560B 0.185434179756865 N548B-S602B 0.185314990782703 S474B-V520B 0.184476661502741 V556B-M590B 0.184253333996272 S471B-C524B 0.183908510475575 F528B-I555B 0.182664711154013 S529B-P560B 0.180719972545728 L523B-S529B 0.180380774313496 S529B-V534B 0.180081759049757 M466B-I472B 0.180054423867293 D554B-L593B 0.179569220734344 M466B-S602B 0.179154593275078 V465B-S602B 0.177512999947405 F530B-F536B 0.177100921794533 I565B-V583B 0.176555915099197 S471B-Y561B 0.176133053824216 V465B-I470B 0.17404672345512 C476B-F587B 0.173227118220209 W527B-R535B 0.172979488665937 F625B-A694B 0.171968072220359 G620B-P698B 0.171395203705038 P560B-I565B 0.170887312315573 N548B-D554B 0.169534321269697 G620B-G689B 0.168060301023305 I472B-R594B 0.167945806293394 F566B-V583B 0.164153030254398 G629B-A694B 0.163875019608181 A557B-T564B 0.163270458336618 N551B-I558B 0.161605379017718 L598B-K603B 0.16089160503937 Y562B-R591B 0.159800165269671 V465B-D554B 0.156301705370448 I470B-I526B 0.155377910060911 V473B-R591B 0.155346740903835 I628B-I693B 0.154876999333903 S529B-I558B 0.154846055138801 G629B-G682B 0.154180439158861 V467B-H601B 0.154115998402672 I552B-I592B 0.153778793943321 M550B-R594B 0.153626476571833 I470B-R594B 0.153616269777171 L621B-P698B 0.151647065633703 P560B-R594B 0.151279201760671 F530B-D554B 0.151145306408642 V584B-R591B 0.150989133092299 S474B-R588B 0.150009058489712 I623B-A688B 0.149656618795274 I519B-I525B 0.149549202333576 N548B-I553B 0.148149581224835 F532B-D554B 0.147908527468039 L621B-G689B 0.146239900706481 E521B-I592B 0.144812034203375 S634B-V681B 0.142681901358438 S464B-E521B 0.141845316690502 F596B-G609B 0.141658869066109 F625B-V630B 0.141365797249644 F596B-G604B 0.141291416361064 N551B-M590B 0.139920206587026 A557B-I586B 0.139068860287526 C524B-S529B 0.138282195828297 S464B-R594B 0.138147828792572 I470B-I519B 0.138104157020528 V467B-I525B 0.137960211705508 Y561B-L593B 0.137114804648966 S471B-W527B 0.135858010268011 I558B-K597B 0.135389612253998 I462B-K597B 0.13426289550455 V520B-I526B 0.134018928063439 S474B-T522B 0.133893030128006 I460B-L469B 0.133655626376673 F528B-R591B 0.132642765811528 F475B-E521B 0.132498762433332 S471B-L523B 0.132282623585196 I468B-H601B 0.130968200609801 S599B-Q606B 0.130771004663684 S474B-R594B 0.127654565583888 K679B-I687B 0.126141306711423 I628B-I687B 0.12577927380996 E531B-N548B 0.125598927886198 T522B-I565B 0.125313681901487 S474B-E521B 0.125283839650422 S635B-A688B 0.124891682016846 V630B-S683B 0.124755520012073 M550B-S599B 0.123549062633304 G609B-M616B 0.123492770971788 I595B-G604B 0.123344077600385 A461B-S529B 0.12316438794497 L469B-W527B 0.122316342811001 F627B-G689B 0.121853786235141 C524B-L533B 0.1214791099528 F633B-G689B 0.120967787167843 L684B-G689B 0.120492234616767 C524B-F596B 0.12047630082332 G620B-I693B 0.120307207923402 F528B-Y562B 0.119743645005153 I553B-L605B 0.119690349633878 I549B-I607B 0.118885279624913 F624B-G689B 0.116305685849397 L608B-L619B 0.116064300650477 L622B-F627B 0.115591158645987 S464B-L523B 0.115411279213646 I631B-G689B 0.115258077041379 S683B-L691B 0.115108523132913 L619B-P698B 0.114755540039508 I628B-F633B 0.114451159419179 L593B-S599B 0.114158802883233 E618B-F624B 0.11408701741104 L621B-A694B 0.114045635080056 I586B-R591B 0.112787198757614 F596B-K603B 0.11172310620393 S635B-L684B 0.11152428800901 W527B-L533B 0.111409764967538 D554B-I559B 0.110787808825497 M466B-C524B 0.110288024314871 E618B-T692B 0.110028444737626 I559B-R591B 0.110020690107553 S615B-A694B 0.109534506311188 L621B-L626B 0.109257065935698 S474B-C524B 0.109103274772486 G629B-V681B 0.108117618067961 I472B-R591B 0.107973326244518 C524B-L593B 0.107114386040752 R617B-P696B 0.106653460036444 L626B-L684B 0.106515314543593 S615B-P696B 0.105904510950465 V534B-M550B 0.104856598160957 V467B-V556B 0.104014211010413 V520B-I525B 0.103997105986815 I468B-I558B 0.103991818717375 V473B-L593B 0.103287628172218 S634B-A686B 0.102954450958178 V534B-D554B 0.102871295754417 M466B-H601B 0.102826722925702 I565B-I586B 0.10264471931555 Y562B-I589B 0.102625963294084 I552B-S599B 0.101726784351486 V473B-A557B 0.101677528862347 E521B-R594B 0.100986928855598 H601B-I607B 0.10097526626191 S634B-L684B 0.100458060087258 G689B-V697B 0.100110316655579 S634B-K679B 0.0995185816555983 M466B-S529B 0.0990079892127937 S529B-I553B 0.0986330269543982 A557B-S599B 0.0986286076641507 V690B-P698B 0.098459697812264 I472B-I592B 0.0983239496562751 S635B-S683B 0.0982259183194927 M616B-L695B 0.0980364473104518 G620B-T692B 0.0972176298140842 L469B-A557B 0.096560640623979 K597B-G604B 0.0957011674622401 I462B-L523B 0.0938017842234385 L469B-S474B 0.0932057901552952 W527B-K597B 0.092681721873848 I459B-L598B 0.0922837426924658 I526B-I558B 0.0922694058831617 M616B-P698B 0.0915347962258306 I460B-L523B 0.0915296330817338 L626B-S634B 0.0913799165395568 I623B-V697B 0.0901161207025528 V465B-I525B 0.0898293125619446 I460B-L533B 0.0897943577203525 L523B-I555B 0.0896700063364853 C476B-I589B 0.0881580465264118 L621B-V690B 0.0880831428994759 E521B-Y562B 0.0879355863247369 L533B-M550B 0.0878618660923218 I595B-Q606B 0.087751682925111 D554B-K597B 0.087200550106836 A686B-A694B 0.0867742021973061 D554B-P560B 0.0864944576895118 A636B-C685B 0.0861258297235463 R594B-L605B 0.0854652560214288 F475B-R591B 0.0854146353391094 V630B-L684B 0.085355717518814 S464B-T522B 0.0847726831401161 I460B-I525B 0.0842597078913996 A636B-A686B 0.084216888834848 L621B-L691B 0.0840978732641195 L469B-L593B 0.0839079364224862 L621B-F627B 0.0838633602028482 M466B-L523B 0.0838290209133428 T522B-I559B 0.0835608562766952 L626B-I631B 0.0833972268856837 S471B-I595B 0.0833909363782119 V563B-F587B 0.0833014774526273 I460B-I470B 0.0818286575975087 M550B-I559B 0.0813935939556902 L632B-A686B 0.0812344593525474 F475B-L523B 0.0811870729250384 C524B-F530B 0.0810003671927682 I468B-I519B 0.0808301124028601 F475B-Y561B 0.0807724250868187 F627B-T692B 0.0806608017864843 S471B-V556B 0.0799563543868063 E521B-Y561B 0.0799048666648976 I460B-H601B 0.0786659130702798 L622B-I687B 0.078338717408418 V467B-L593B 0.0779856002383068 T564B-M590B 0.0776677092048113 Y561B-Q585B 0.0775245370594649 I519B-W527B 0.0774859437457937 N548B-S599B 0.0770993674605083 V465B-T522B 0.0770359676226224 S464B-A557B 0.0764958664112005 A557B-I565B 0.0764485775479296 V465B-I592B 0.0763845524880402 V563B-I589B 0.0763195640210874 M466B-I595B 0.0755799314043148 I462B-I595B 0.0751998562795511 V473B-L523B 0.075127560336005 L632B-G689B 0.0747965620520556 N551B-R591B 0.0746817484898679 L608B-V697B 0.0746738706848804 L533B-I559B 0.0740924309804885 V556B-L598B 0.0735724356406207 L567B-R588B 0.0729239501657039 I526B-D554B 0.072618613552381 S464B-I525B 0.072540110027087 I565B-M590B 0.0724757356460759 A688B-L695B 0.0724386522648484 L622B-V690B 0.0713289437769422 I628B-C685B 0.0706248565733705 C476B-R594B 0.0703850947835374 L593B-R600B 0.0703817473737529 E521B-I565B 0.06993835287828 F627B-L632B 0.0698605941507964 S634B-A688B 0.0696667965147544 V463B-H601B 0.0683457344573952 Q585B-L593B 0.0682814133845673 I565B-Q585B 0.068241215649316 V467B-I472B 0.0680876476313719 L632B-I687B 0.0680092985177767 V563B-R591B 0.0678045604425606 I549B-L608B 0.0676054322845523 S529B-Y561B 0.0675914180711183 F517B-T564B 0.0674876898055625 L626B-A636B 0.0671839134453514 S471B-I592B 0.0671484505879869 R617B-P698B 0.0669268123078908 Q606B-S615B 0.0666317457299033 F530B-I559B 0.0664279322392745 S474B-I525B 0.0656767180914852 I468B-S529B 0.0655388990916372 F517B-I526B 0.0652880101294588 V463B-R600B 0.0652658801567052 L469B-F517B 0.0650893141233939 R535B-A557B 0.0648570083876329 M550B-I595B 0.064356914821726 N548B-G609B 0.0643176557573195 E531B-M550B 0.0642209315414662 L523B-I559B 0.0639976992203017 I553B-Y561B 0.063764116484168 F530B-I552B 0.0634955884210351 T564B-R591B 0.0634659262306584 A461B-F530B 0.0634334156453349 F532B-N551B 0.063405890733673 F625B-A686B 0.0632634405743313 F475B-I586B 0.062964961037939 N551B-S602B 0.0629640294300025 H601B-G609B 0.0629534176556832 I460B-F532B 0.0627802400404984 I470B-W527B 0.0623899463422317 F627B-F633B 0.0622162784027456 L621B-I693B 0.0615737122131619 Y561B-R594B 0.0613966949507176 I519B-F528B 0.0611027190941886 A461B-R535B 0.0608619128575879 S464B-S599B 0.0604574606320851 N551B-V556B 0.0594533218022244 I631B-V681B 0.059140443597185 I470B-V520B 0.0589828433041015 R535B-I555B 0.0589314064861901 I468B-F517B 0.0587490500633532 V463B-I525B 0.0587074706225126 I468B-E531B 0.0584188144857309 I472B-R588B 0.05806364381044 L621B-G629B 0.0578357073378702 T522B-A557B 0.0577378797638222 F536B-I553B 0.0572841037335206 A686B-I693B 0.0569736081130996 I553B-I595B 0.0568988850862597 F528B-N551B 0.0565016060038337 I470B-K597B 0.0559526127806258 E521B-T564B 0.0559305382580995 F528B-I595B 0.0556154966694271 S464B-I526B 0.0555489688297484 R535B-I552B 0.0554548518134934 I552B-R600B 0.0554010160366186 G620B-A694B 0.0552733414241162 S683B-T692B 0.0552377412633751 I470B-F596B 0.0551188087080837 S464B-D554B 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