1F8E (resolution: 1.40 Å)

ID Name Organism Chains bound to carbohydrates
1 Neuraminidase
P03472 (NRAM_I75A5)
CAZy family: GH34
Influenza A virus (A/tern/Australia/G70C/1975(H11N9)) 1 chain bound to carbohydrates
Chain A:
2 binding sites
3 glycosylation head interfaces
1 glycosylation body interface
3 N-glycosylations

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains Binding affinity
2 α-D-mannopyranose-(1-2)-α-D-mannopyranose-(1-2)-α-D-mannopyranose-(1-3)-[α-D-mannopyranose-(1-6)]α-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 2 (1 molecule) A
3 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 3 (3 molecules) A
5 4 + 9-amino-2 + 4-deoxy-2 + 3-dehydro-N-acetyl-neuraminic acid 1 (1 molecule) A Ki=15uM (MOAD),-logKd/Ki=4.82, Ki=15uM (PDBbind-CN)

Binding sites


Related structures