1SYO (resolution: 2.20 Å)

ID Name Organism Chains bound to carbohydrates
1 Cation-independent mannose-6-phosphate receptor
P08169 (MPRI_BOVIN)
Unilectin fold: b-barrel
Unilectin class: P-type lectin
Unilectin family: CI-MPR
Bos taurus 2 chains bound to carbohydrates
Chain A:
2 binding sites
2 glycosylation head interfaces
2 glycosylation body interfaces
1 N-glycosylation
1 unassigned-glycosylation
Chain B:
2 binding sites
2 glycosylation head interfaces
2 unassigned-glycosylations

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains Binding affinity
2 β-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-α-D-glucopyranose 3 (1 molecule) A
3 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 3 (3 molecules) A, B
4 6-O-phosphono-α-D-mannopyranose 2 (2 molecules) A, B Kd~1nM (MOAD),-logKd/Ki=9.00, Kd~1nM (PDBbind-CN)

Binding sites


Related structures


Bound to carbohydrates
Without carbohydrates