2V8W (resolution: 2.30 Å)

ID Name Organism Chains bound to carbohydrates
1 Eukaryotic translation initiation factor 4E
P06730 (IF4E_HUMAN)
HOMO SAPIENS 2 chains bound to carbohydrates
Chain A:
1 binding site
Chain C [auth E]:
1 binding site
2 Eukaryotic translation initiation factor 4E-binding protein 1
Q13541 (4EBP1_HUMAN)
HOMO SAPIENS 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
3 [[(2r + 3S + 4r + 5r)-5-(6-amino-3-methyl-4-oxo-5h-imidazo[4 + 5-C]pyridin-1-yl)-3 + 4-dihydroxy-oxolan-2-yl]methoxy-hydroxy-phosphoryl] phosphono hydrogen phosphate 2 (2 molecules) A, C
[auth A,E]
Kd=146nM (MOAD)

Binding sites


Related structures