4Q1S (resolution: 2.60 Å)

ID Name Organism Chains bound to carbohydrates
1 Proteasome subunit alpha type-2
P23639 (PSA2_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
2 Proteasome subunit alpha type-3
P23638 (PSA3_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
3 Proteasome subunit alpha type-4
P40303 (PSA4_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
4 Proteasome subunit alpha type-5
P32379 (PSA5_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
5 Proteasome subunit alpha type-6
P40302 (PSA6_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
6 Probable proteasome subunit alpha type-7
P21242 (PSA7_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
7 Proteasome subunit alpha type-1
P21243 (PSA1_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
8 Proteasome subunit beta type-2
P25043 (PSB2_YEAST)
Saccharomyces cerevisiae 2 chains bound to carbohydrates
Chain H:
2 glycosylation head interfaces
1 unassigned-glycosylation
Chain V:
2 glycosylation head interfaces
1 unassigned-glycosylation
9 Proteasome subunit beta type-3
P25451 (PSB3_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
10 Proteasome subunit beta type-4
P22141 (PSB4_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
11 Proteasome subunit beta type-5
P30656 (PSB5_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
12 Proteasome subunit beta type-6
P23724 (PSB6_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates
13 Proteasome subunit beta type-7
P30657 (PSB7_YEAST)
Saccharomyces cerevisiae 2 chains bound to carbohydrates
Chain M:
2 glycosylation head interfaces
Chain AA [auth a]:
2 glycosylation head interfaces
14 Proteasome subunit beta type-1
P38624 (PSB1_YEAST)
Saccharomyces cerevisiae 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
15 (5r + 6r + 7S + 8r + 9r + 12S + 13e + 16S + 18S + 19r + 20ar)-4 + 7 + 19-trihydroxy-2 + 6 + 8 + 12 + 14 + 16 + 18-heptamethyl-6 + 7 + 8 + 9 + 10 + 11 + 12 + 15 + 16 + 17 + 18 + 19 + 20 + 20α-tetradecahydro-1 + 19:5 + 9-diepoxybenzo[18]annulen-3(5h)-one 4 (2 molecules) AA, H, M, V
[auth H,M,V,a]
-logKd/Ki=4.17, IC50=67.9uM (PDBbind-CN) ;

Binding sites


Related structures


Bound to carbohydrates
Without carbohydrates