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6U9K
(resolution: 2.00 Å)
Select a model
Model 1
ID
Name
Organism
Chains bound to carbohydrates
1
Histone-lysine N-methyltransferase 2A
Q03164
(KMT2A_HUMAN)
Homo sapiens
2 chains bound to carbohydrates
Chain A
:
1 binding site
Chain B
:
1 binding site
Chain properties
This chain feature no protein-carbohydrate interface.
Entity 1 (Histone-lysine N-methyltransferase 2A )
A
B
Carbohydrates
ID
Description
N° of binding sites
Bound to chains
Binding affinity
3
5'-([(3S)-3-amino-3-carboxypropyl]{[1-(3 + 3-diphenylpropyl)azetidin-3-yl]methyl}amino)-5'-deoxyadenosine
2 (2 molecules)
A, B
ic50=138.4nM (MOAD)
Binding sites
Select a binding site
(Entity 3 - molecule 1) -- 6U9K_1_Q2V_1 -- Q2V4002:A -- bound to chain A -- Cluster not attributed--
(free)
-- 43 atoms and SASA 426 A²
(Entity 3 - molecule 2) -- 6U9K_1_Q2V_2 -- Q2V4003:B -- bound to chain B -- Cluster not attributed--
(free)
-- 47 atoms and SASA 451 A²
Related structures
Bound to carbohydrates
6PWW
2W5Z
6U9M
5F6L
2W5Y
5F5E
6KIU
6KIV
6KIX
6KIZ
6PWV
6U9K
6U9N
6U9R
7RZJ
7W67
7W6A
7W6I
7W6J
Without carbohydrates
2KKF
2AGH
2J2S
2JYI
2KU7
2KYU
2LXS
2LXT
2MSR
2MTN
3EG6
3EMH
3LQH
3LQI
3LQJ
3P4F
3U85
3U88
4ESG
4GQ6
4NW3
5SVH
6EMQ
6W5I
6W5M
6W5N
7MBM
7MBN
7RZD
7S79
7S7D
7S8A
7S8E
7S8F
7ZEY
7ZEZ