7MN8 (resolution: 3.45 Å)

ID Name Organism Chains bound to carbohydrates
1 Receptor tyrosine-protein kinase erbB-3
P21860 (ERBB3_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
5 glycosylation head interfaces
2 glycosylation body interfaces
5 N-glycosylations
2 Pro-neuregulin-1, membrane-bound isoform
Q02297 (NRG1_HUMAN)
Homo sapiens 0 chain bound to carbohydrates
3 Receptor tyrosine-protein kinase erbB-2,Maltose/maltodextrin-binding periplasmic protein
P04626, P0AEX9
Homo sapiens 1 chain bound to carbohydrates
Chain C [auth B]:
3 glycosylation head interfaces
3 glycosylation body interfaces
3 N-glycosylations
4 Trastuzumab Fab Light Chain
Light chain subclass: IGKV1 (Kappa)
Homo sapiens 0 chain bound to carbohydrates
5 Trastuzumab Fab Heavy Chain
Heavy chain subclass: IGHV3
Homo sapiens 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains
6 il-7racdw127 2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 4 (2 molecules) A
7 α-D-mannopyranose-(1-3)-β-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 4 (1 molecule) C
[auth B]
8 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 5 (5 molecules) A, C
[auth A,B]

Binding sites


Related structures