2FAP (resolution: 2.20 Å)

ID Name Organism Chains bound to carbohydrates
1 Peptidyl-prolyl cis-trans isomerase FKBP1A
P62942 (FKB1A_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
1 binding site
2 Serine/threonine-protein kinase mTOR
P42345 (MTOR_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain B:
1 binding site

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
3 C49-methyl rapamycin 1 (1 molecule) A, B Ki=4nM, EC50=200nM (BindingDB)

Binding sites


Related structures