6M4U (resolution: 2.20 Å)

ID Name Organism Chains bound to carbohydrates
1 Peptidyl-prolyl cis-trans isomerase FKBP1A
P62942 (FKB1A_HUMAN)
Homo sapiens 2 chains bound to carbohydrates
Chain A:
1 binding site
Chain C [auth E]:
1 binding site
2 Serine/threonine-protein kinase mTOR
P42345 (MTOR_HUMAN)
Homo sapiens 2 chains bound to carbohydrates
Chain B:
1 binding site
Chain D [auth F]:
1 binding site

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
3 rapamycin immunosuppressant drug 2 (2 molecules) A, B, C, D
[auth A,B,E,F]
IC50=0.600000nM, EC50=30nM, Ki=0.20nM (BindingDB)

Binding sites


Related structures