4EMT (resolution: 1.50 Å)

ID Name Organism Chains bound to carbohydrates
1 Stimulator of interferon genes protein
Q86WV6 (STING_HUMAN)
Homo sapiens 2 chains bound to carbohydrates
Chain A:
2 binding sites
Chain B:
2 binding sites

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
2 9 + 9'-[(2r + 3r + 3as + 5S + 7ar + 9r + 10r + 10as + 12S + 14ar)-3 + 5 + 10 + 12-tetrahydroxy-5 + 12-dioxidooctahydro-2h + 7h-difuro[3 + 2-D:3' + 2'-j][1 + 3 + 7 + 9 + 2 + 8]tetraoxadiphosphacyclododecine-2 + 9-diyl]bis(2-amino-1 + 9-dihydro-6h-purin-6-one) 2 (1 molecule) A, B Kd=5uM (22728658) (BioLiP),Kd=4.63uM (MOAD),-logKd/Ki=5.30, Kd~5uM (PDBbind-CN),EC50=4500nM, Kd=1210nM (BindingDB)

Binding sites


Related structures