6YDZ (resolution: 2.90 Å)

ID Name Organism Chains bound to carbohydrates
1 Stimulator of interferon genes protein
Q86WV6 (STING_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
2 binding sites

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
2 2-amino-9-[(2r + 3r + 3as + 5r + 7ar + 9r + 10r + 10as + 12r + 14ar)-9-(6-amino-9h-purin-9-yl)-3 + 5 + 10 + 12-tetrahydroxy-5 + 12-dioxidooctahydro-2h + 7h-difuro[3 + 2-D:3' + 2'-j][1 + 3 + 7 + 9 + 2 + 8]tetraoxadiphosphacyclododecin-2-yl]-1 + 9-dihydro-6h-purin-6-one 2 (1 molecule) A EC50=120nM, Kd=1040nM (BindingDB)

Binding sites


Related structures