5HYN (resolution: 2.94 Å)

ID Name Organism Chains bound to carbohydrates
1 Histone-lysine N-methyltransferase EZH2
Q15910 (EZH2_HUMAN)
Homo sapiens 4 chains bound to carbohydrates
Chain A:
1 binding site
Chain F:
1 binding site
Chain K:
1 binding site
Chain P [auth Q]:
1 binding site
2 Polycomb protein EED
O75530 (EED_HUMAN)
Homo sapiens 0 chain bound to carbohydrates
3 Polycomb protein SUZ12
Q15022 (SUZ12_HUMAN)
Homo sapiens 0 chain bound to carbohydrates
4 Histone H3.1
P68431 (H31_HUMAN)
Homo sapiens 0 chain bound to carbohydrates
5 Protein Jumonji
Q92833 (JARD2_HUMAN)
Homo sapiens 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
7 S-adenosyl-L-homocysteine 4 (4 molecules) A, F, K, P
[auth A,F,K,Q]
IC50=467nM (BindingDB)

Binding sites


Related structures


Bound to carbohydrates
Without carbohydrates