7AT8 (resolution: 4.40 Å)

ID Name Organism Chains bound to carbohydrates
1 Histone-lysine N-methyltransferase EZH2
Q15910 (EZH2_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
1 binding site
2 Polycomb protein SUZ12
Q15022 (SUZ12_HUMAN)
Homo sapiens 0 chain bound to carbohydrates
3 Histone H3.2
P84233 (H32_XENLA)
Xenopus laevis 1 chain bound to carbohydrates
Chain C [auth D]:
1 binding site
4 Histone H4
P62799 (H4_XENLA)
Xenopus laevis 0 chain bound to carbohydrates
5 Histone H2A type 1
P06897 (H2A1_XENLA)
Xenopus laevis 0 chain bound to carbohydrates
6 Histone H2B 1.1
P02281 (H2B11_XENLA)
Xenopus laevis 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
10 S-adenosyl-L-homocysteine 1 (1 molecule) A, C
[auth A,D]
IC50=467nM (BindingDB)

Binding sites


Related structures