5M7S (resolution: 2.40 Å)

ID Name Organism Chains bound to carbohydrates
1 Protein O-GlcNAcase
O60502 (OGA_HUMAN)
CAZy family: GH84
Homo sapiens 2 chains bound to carbohydrates
Chain A:
2 binding sites
Chain B:
2 binding sites

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
2 (3ar + 5r + 6S + 7r + 7ar)-2-(ethylamino)-5-(hydroxymethyl)-5 + 6 + 7 + 7α-tetrahydro-3ah-pyrano[3 + 2-D][1 + 3]thiazole-6 + 7-diol 2 (2 molecules) A, B Ki=0.9nM (MOAD),-logKd/Ki=9.05, Ki=0.9nM (PDBbind-CN),Ki=21nM, EC50=13nM, IC50=0.410000nM (BindingDB)

Binding sites


Related structures


Bound to carbohydrates
Without carbohydrates