6CKC (resolution: 2.80 Å)

ID Name Organism Chains bound to carbohydrates
1 Protein arginine N-methyltransferase 5
O14744 (ANM5_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
1 binding site
2 Methylosome protein WDR77
Q9BQA1 (MEP50_HUMAN)
Homo sapiens 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
3 7-[(5r)-5-C-phenyl-β-D-ribofuranosyl]-7h-pyrrolo[2 + 3-D]pyrimidin-4-amine 1 (1 molecule) A -logKd/Ki=8.22, Kd=6nM (PDBbind-CN),IC50=25nM, Kd=6.0nM, EC50=40nM (BindingDB)

Binding sites


Related structures