6K1S (resolution: 2.60 Å)

ID Name Organism Chains bound to carbohydrates
1 Protein arginine N-methyltransferase 5
O14744 (ANM5_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
1 glycosylation head interface
1 S-glycosylation
2 Methylosome protein WDR77
Q9BQA1 (MEP50_HUMAN)
Homo sapiens 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
3 2-[[7-[(2~{r} + 3~{r} + 4~{S} + 5~{r})-5-[(~{r})-(4-chlorophenyl)-oxidanyl-methyl]-3 + 4-bis(oxidanyl)oxolan-2-yl]pyrrolo[2 + 3-D]pyrimidin-4-yl]amino]ethanal 1 (1 molecule) A -logKd/Ki=7.70, IC50=0.020uM (PDBbind-CN),IC50=20nM (BindingDB)

Binding sites


Related structures