6DJP (resolution: 4.80 Å)

ID Name Organism Chains bound to carbohydrates
1 Integrin alpha-V
P06756 (ITAV_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
6 glycosylation head interfaces
7 glycosylation body interfaces
5 N-glycosylations
2 Integrin beta-8
P26012 (ITB8_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain B:
5 glycosylation head interfaces
4 glycosylation body interfaces
5 N-glycosylations
3 8B8 heavy chain Fab
Heavy chain subclass: IGHV3
Mus musculus 0 chain bound to carbohydrates
4 8B8 light chain Fab
Light chain subclass: IGKV4 (Kappa)
Mus musculus 0 chain bound to carbohydrates
5 68 heavy chain Fab
Heavy chain subclass: IGHV1
Mus musculus 1 chain bound to carbohydrates
Chain E:
1 glycosylation head interface
6 68 light chain Fab
Light chain subclass: IGKV10 (Kappa)
Mus musculus 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains
7 il-7racdw127 2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 12 (6 molecules) A, B, E
8 α-D-mannopyranose-(1-4)-α-D-mannopyranose-(1-6)-[α-D-mannopyranose-(1-3)]β-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 5 (1 molecule) A
9 il-7racdw127 β-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 2 (1 molecule) B
10 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 2 (2 molecules) A, B

Binding sites


Related structures