7U60 (resolution: 2.55 Å)

ID Name Organism Chains bound to carbohydrates
1 Integrin alpha-IIb
P08514 (ITA2B_HUMAN)
Homo sapiens 2 chains bound to carbohydrates
Chain A:
1 glycosylation head interface
3 glycosylation body interfaces
Chain C:
1 glycosylation head interface
3 glycosylation body interfaces
2 Integrin beta-3
P05106 (ITB3_HUMAN)
Homo sapiens 2 chains bound to carbohydrates
Chain B:
3 glycosylation head interfaces
2 glycosylation body interfaces
3 N-glycosylations
Chain D:
3 glycosylation head interfaces
2 glycosylation body interfaces
3 N-glycosylations
3 Fab heavy chain
Heavy chain subclass: IGHV14
Mus musculus 0 chain bound to carbohydrates
4 Fab light chain
Light chain subclass: IGKV14 (Kappa)
Mus musculus 0 chain bound to carbohydrates
5 ARG-GLY-ASP-DPN-VAL synthetic construct 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains
6 α-D-mannopyranose-(1-3)-α-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 8 (2 molecules) A, B, C, D
7 il-7racdw127 2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 4 (2 molecules) B, D
12 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 2 (2 molecules) B, D

Binding sites


Related structures