1YY9 (resolution: 2.60 Å)

ID Name Organism Chains bound to carbohydrates
1 Epidermal growth factor receptor
P00533 (EGFR_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
8 glycosylation head interfaces
6 glycosylation body interfaces
8 N-glycosylations
2 Cetuximab Fab Light chain
Light chain subclass: IGKV5 (Kappa)
Mus musculus, Homo sapiens 0 chain bound to carbohydrates
3 Cetuximab Fab Heavy chain
Heavy chain subclass: IGHV2
Mus musculus, Homo sapiens 1 chain bound to carbohydrates
Chain C [auth D]:
1 glycosylation head interface
1 N-glycosylation

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains
4 α-D-mannopyranose-(1-2)-α-D-mannopyranose-(1-6)-[α-D-mannopyranose-(1-3)]α-D-mannopyranose-(1-6)-[α-D-mannopyranose-(1-3)-α-D-mannopyranose-(1-3)]β-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 4 (1 molecule) A
5 il-7racdw127 2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 6 (3 molecules) A
6 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 5 (5 molecules) A, C
[auth A,D]

Binding sites


Related structures