5XWD (resolution: 2.89 Å)

ID Name Organism Chains bound to carbohydrates
1 Epidermal growth factor receptor
P00533 (EGFR_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
8 glycosylation head interfaces
3 glycosylation body interfaces
8 N-glycosylations
2 VH chain of 059-152
Heavy chain subclass: IGHV4
Homo sapiens 1 chain bound to carbohydrates
Chain B [auth H]:
1 glycosylation head interface
4 glycosylation body interfaces
3 VL chain of 059-152
Light chain subclass: IGLV3 (Lambda)
Homo sapiens 1 chain bound to carbohydrates
Chain C [auth D]:
1 glycosylation head interface

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains
4 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose-(1-2)-α-D-mannopyranose-(1-3)-[2-acetamido-2-deoxy-β-D-glucopyranose-(1-2)-α-D-mannopyranose-(1-6)]β-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 5 (1 molecule) A, B
[auth A,H]
5 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 7 (7 molecules) A, C
[auth A,D]

Binding sites


Related structures