6B3S (resolution: 2.79 Å)

ID Name Organism Chains bound to carbohydrates
1 Epidermal growth factor receptor
P00533 (EGFR_HUMAN)
Homo sapiens 4 chains bound to carbohydrates
Chain A:
4 glycosylation head interfaces
3 glycosylation body interfaces
4 N-glycosylations
Chain D [auth B]:
4 glycosylation head interfaces
4 glycosylation body interfaces
4 N-glycosylations
Chain G [auth E]:
4 glycosylation head interfaces
4 glycosylation body interfaces
4 N-glycosylations
Chain J [auth I]:
3 glycosylation head interfaces
2 glycosylation body interfaces
3 N-glycosylations
2 Necitumumab Fab Heavy chain
Heavy chain subclass: IGHV4
Homo sapiens 0 chain bound to carbohydrates
3 Necitumumab Fab Light chain
Light chain subclass: IGKV3 (Kappa)
Homo sapiens 0 chain bound to carbohydrates

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains
4 il-7racdw127 2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 10 (5 molecules) A, D, G, J
[auth A,B,E,I]
5 il-7racdw127 β-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 3 (1 molecule) A
6 α-D-mannopyranose-(1-3)-β-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 8 (2 molecules) D, G
[auth B,E]
7 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 7 (7 molecules) A, D, G, J
[auth A,B,E,I]

Binding sites


Related structures