4KRO (resolution: 3.05 Å)

ID Name Organism Chains bound to carbohydrates
1 Epidermal growth factor receptor
P00533 (EGFR_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
4 glycosylation head interfaces
2 glycosylation body interfaces
4 N-glycosylations
2 Nanobody/VHH domain EgA1
Heavy chain subclass: IGHV1
Lama glama 0 chain bound to carbohydrates
3 Cetuximab light chain
Light chain subclass: IGKV5 (Kappa)
Mus musculus, Homo sapiens 0 chain bound to carbohydrates
4 Cetuximab heavy chain
Heavy chain subclass: IGHV2
Mus musculus, Homo sapiens 1 chain bound to carbohydrates
Chain D:
1 glycosylation head interface
1 N-glycosylation

Chain properties


Carbohydrates


ID Common name Description N° of binding sites Bound to chains
5 il-7racdw127 2-acetamido-2-deoxy-β-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-β-D-glucopyranose 4 (2 molecules) A
6 zn-α-2-glycoprotein zag 2-acetamido-2-deoxy-β-D-glucopyranose 3 (3 molecules) A, D

Binding sites


Related structures