3QOX (resolution: 2.30 Å)

ID Name Organism Chains bound to carbohydrates
1 Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3 (DOT1L_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
1 binding site

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
2 S-adenosyl-L-homocysteine 1 (1 molecule) A Ki=0.27uM (MOAD),-logKd/Ki=6.57, Ki=0.27uM (PDBbind-CN),Ki=160nM, IC50=600nM, Kd=150nM (BindingDB)

Binding sites


Related structures