4WVL (resolution: 2.40 Å)

ID Name Organism Chains bound to carbohydrates
1 Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3 (DOT1L_HUMAN)
Homo sapiens 1 chain bound to carbohydrates
Chain A:
1 binding site

Chain properties


Carbohydrates


ID Description N° of binding sites Bound to chains Binding affinity
2 N-[4-(acetylamino)butyl]-5'-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(propan-2-yl)amino]-5'-deoxyadenosine 1 (1 molecule) A -logKd/Ki=6.88, Kd=131nM (PDBbind-CN)

Binding sites


Related structures