4EKG (resolution: 2.80 Å)

ID Name Organism Chains bound to carbohydrates
1 Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3 (DOT1L_HUMAN)		 Homo sapiens 1 chain bound to carbohydrates
Chain A:
1 binding site

Chain properties

Carbohydrates

ID Description N° of binding sites Bound to chains Binding affinity
2 5'-[(3-{[(4-tert-butylphenyl)carbamoyl]amino}propyl)(methyl)amino]-5'-deoxyadenosine 1 (1 molecule) A -logKd/Ki=8.77, Kd=1.7nM (PDBbind-CN),Ki=13nM (BindingDB)

Binding sites

Related structures

Bound to carbohydrates
Without carbohydrates