3UWP (resolution: 2.05 Å)

ID Name Organism Chains bound to carbohydrates
1 Histone-lysine N-methyltransferase, H3 lysine-79 specific
Q8TEK3 (DOT1L_HUMAN)		 Homo sapiens 1 chain bound to carbohydrates
Chain A:
1 binding site

Chain properties

Carbohydrates

ID Description N° of binding sites Bound to chains Binding affinity
2 (2r + 3r + 4S + 5r)-2-(4-amino-5-iodo-7h-pyrrolo[2 + 3-D]pyrimidin-7-yl)-5-(hydroxymethyl)tetrahydrofuran-3 + 4-diol 1 (1 molecule) A IC50=7000nM (BindingDB)

Binding sites

Related structures

Bound to carbohydrates
Without carbohydrates